Is
a Covid counseled patient likely to become infected again?
Millions
of people around the world have been diagnosed with Covid-19, and one of their
biggest worries is that they may be infected again with the coronavirus.
Have they developed
immunity and if so, for how long?
There
have been a number of cases of people being said to be positive, re-tested for
HIV, and raised fears of re-infection. At present, scientists cannot say how
re-infection is possible and if so, after how long. And they are not sure if a
person with the virus gets infected again. A new guide from the Centers for Disease
Control and Prevention (CDC) in the United States is trying to answer some of
these questions by highlighting new information from recent research.
What is the Centers of Disease
Control and Prevention (CDC) guidance?
In
a statement issued at the end of the week, the CDC, which is part of the US
Department of Health, said no confirmed cases of re-infection had been found so
far. The re-entry of SARS-CoV-2 has not been explicitly confirmed by anyone who
has resigned so far. If, and in that case, people can re-contract the
SARS-CoV-2 virus it remains unknown, and it is a matter that is being
investigated, ”said the CDC. However, this does not mean that people who have
been infected with the virus can be said to open up the immune system to fight
back.
What about recovered
patients who have tested positive again?
The
Centers for Disease Control and Prevention (CDC) states that an overweight
patient may have a low viral load for up to three months after his or her first
diagnosis, and this may be found in diagnostic tests. This is the reason why
there are recovery times for people who are re-tested within a period of three
months. But such people do not transmit the virus to others. Therefore,
re-insertion within three months was not appropriate. Even if they are tested
for HIV, it is more likely to be the result of the left viral infection
(“recurrent infection”) rather than a case of re-infection.
People
who have been diagnosed can continue to inject SARS-CoV-2RNA into the
respiratory tract up to three months after the illness set, however at a much
lower concentration than during the illness, in stages where the virus is more
likely to replicate (which can replicate and spread). (cause of the disease) of
this ongoing SARS-CoV-2RNA.The study found no evidence that clinically people
recover people who persist with viral RNA and transmit others to SARS-CoV-2.
What else do the guidelines
say?
The
Centers of Disease Control and Prevention (CDC) said that persons with mild to
moderate symptoms can be released from isolation 10 days after the they were
first tested positive, while those with severe symptoms need to be kept in
isolation for a maximum of 20 days. “Available data indicate that persons with mild
to moderate COVID-19 remain infectious no longer than 10 days after symptom on set.
Persons with more severe to critical illness or severe immunocompromise likely
remain infectious no longer than 20 days after symptom onset.
The
Centers of Disease Control and Prevention (CDC) said its new recommendations
were based on more than 15 international and US-based published studies that looked
at the length of infection, duration of viral shed, asymptomatic spread, and
the risk of spread among various patient groups. “Researchers have found that
the amount of live virus in the nose and throat drops significantly soon after
the COVID19 symptoms develop. Additionally, the duration of infectiousness in
most people with COVID19 is no longer than 10 days after symptoms begin and no longer
than 20days in people with severe illness.
It said the latest findings strengthened the
case for relying on “symptom-based, rather than test-based strategy for ending isolation”
of infected patients, so that persons who are “by current evidence no longer infectious
are not kept unnecessarily isolated and excluded from work or other
responsibilities.
Preliminary analysis
suggests plasma therapy is effective
Preliminary
analysis of further research of 300+ Covid-19 patients suggests that
convalescent plasma therapy is effective, in which patients were treated. The
results of the first analysis were published on March 28 and became the first
medical center in the United States to include Covid-19 patients who were
critically ill with plasma donated to counseled patients. Since then,
researchers have used 350 patients' treatments. The analysis measured the
effectiveness of the treatment.
It
provides scientific evidence that transporting critically ill Covid-19 patients
with high pre-hospital plasma - within 72 hours of hospital admission that
proves highly effective - has reduced mortality rates. Those who were treated
earlier with plasma with higher anti-Covid-19 antibodies, the study found, were
more likely to survive and recover than the same patients who could be treated
with plasma. This study excluded patients with a history of severe blood
transfusion reactions, those without chronic and inevitable termination of the
disease, and patients with full swelling or other conditions that would
increase the risk of plasma transfusions.
In heart cells, it shows
why Covid is difficult for older people
Researchers
have published findings that provide clues as to why Covid-19 infection tends
to get worse over the years. Certain genes in the body, which play a key role
in allowing the novel coronavirus SARS-CoV-2 to invade heart cells, are more
active with age, according to a study published in the Jourism of Molecular and
Cellular Cardiology.
When
the novel coronavirus first appeared, it was considered a major respiratory
disease. But as research has continued, it has become clear that Covid-19
patients, especially the elderly, are also affected by heart problems. An
overseas team of investigators investigated the link between Covid-19 and heart
failure. Specifically, they examine cells called cardiomyocytes, which make up
the heart muscle and are able to break down and relax. Damage to these cells
can lead to heart failure.
Researchers
compared cardiomyocytes from five young men (ages 19–25) and five adult males
(63-78). They found that the genes that provide the body's instructions for
making the essential proteins that those viruses rent to the cell - including
ACE2 receptors now - were more active in adult male in cardiomyocytes. This
suggests that there may be an increase in the associated protein in older
cardiomyocytes.
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