How human immune response system works


How human immune response system works

In T cells, clues why some immune responses stronger

Researchers calculate that T cells of people who have recovered from mild to moderate Covid-19 cases. Their study, published in Cell Reports Medicine, sheds light on how effective immune responses to SARS CoV-2 can be in improving vaccine development. The immune response to SARS-CoV-2 can be through the use of both antibodies or T cells. The researchers used a process called CyTOF, which regulates T cells according to their protein content. They said they found patterns found in specialized SARS-CoV-2 cells that could explain how these patients recovered from Covid-19.

Covid-related disorder alters immune system in kids

A small number of children with Covid-19 have developed a disease called pediatric immune system syndrome (PIMS-TS). A rare disease causes severe inflammation of the blood vessels and can lead to heart damage. UK researchers analyzed blood samples from 25 children with PIMS-TS and compared them with healthy children. A study, published in Nature Medicine, found that in the severe phase of PIMS-TS, children increased levels of cytokines immune) and reduced levels of white blood cells called lymphocytes. By the time the children are older, the immune system has slowly returned. Researchers say the study provides important evidence for future research and will show what treatment is most likely to help patients with that condition.

T cell response stronger in women patients of Covid

DURING the Covid19 epidemic, studies have repeatedly shown that the disease is more severe in men than in women, and it is more lethal in men. Various reasons have been proposed for this. A new study published in the journal Nature on Wednesday provided another clue — that women increase the strength and stamina of immune cells by T cells. This new study examined 98 patients admitted to Yale New Haven Hospital in the US for mild to moderate Covid-19. It is the first study to look at sex-responsive immune responses in the novel coronavirus SARS-CoV-2.

When a virus or pathogen invades the body, the immune system can fight off the invader by invading cells, or Tcell cells, which are a type of white blood cell. T cells that can fight off invading cells are already infected. Alternatively, they can act as “helper cells” by helping the body's cells produce antibodies. For women, a new study found that Tcell's response was stronger. Researchers say the study could help guide a sex-based approach to Covid 19 treatment. Also, poor T cell response is related to age-related inconsistencies in male patients. In other words, older men had a mild T cell response than younger men, and they showed that the worst disease had come out. This was not the case for female patients.

A model for treating two patients with one ventilator

A new study shows that flexible ventilators can help two patients simultaneously in the event of a shortage. Researchers from King's College London and Imperial College London have developed a model on how one ventilator can be used to treat two patients. Although separating ventilators can be dangerous in nature, the researchers say their model shows that some of the obstacles can be reduced. The model uses different imbalances and one-way valves. Depression brought on in one patient can be enslaved independently of another. This approach could be useful in treating Covid-19 patients, as well as in other cases - including the condition of military warfare, researchers said. A new study is published in the Royal Society Open Science.


Most common symptoms of Coronavirus
v  Fever
v  Dry cough
v  Tiredness
Less common symptoms of Coronavirus
v  Aches and pains
v  Sore throat
v  Diarrhea
v  Conjunctivitis
v  Headache
v  Loss of taste or smell

v  A rash on skin, or discolouration of fingers or toes

To prevent the spread of COVID-19:
      Clean your hands often. Use soap and water, or an alcohol-based hand rub.
Maintain a safe distance from anyone who is coughing or sneezing.
Wear a mask when physical distancing is not possible.
Don’t touch your eyes, nose or mouth.
Cover your nose and mouth with your bent elbow or a tissue when you cough or sneeze.
Stay home if you feel unwell.
If you have a fever, cough and difficulty breathing, seek medical attention.Calling in advance allows your healthcare provider to quickly direct you to the right health facility. This protects you, and prevents the spread of viruses and other infections.
Masks - Masks can help prevent the spread of the virus from the person wearing the mask to others. Masks alone do not protect against COVID-19, and should be combined with physical distancing and hand hygiene. Follow the advice provided by your local health authority.

Self-care
     If you feel sick you should rest, drink plenty of fluid, and eat nutritious food. Stay in a separate room from other family members, and use a dedicated bathroom if possible. Clean and disinfect frequently touched surfaces.
    Everyone should keep a healthy lifestyle at home. Maintain a healthy diet, sleep, stay active, and make social contact with loved ones through the phone or internet. Children need extra love and attention from adults during difficult times. Keep to regular routines and schedules as much as possible.
     It is normal to feel sad, stressed, or confused during a crisis. Talking to people you trust, such as friends and family, can help. If you feel overwhelmed, talk to a health worker or counselor.

HOW IT SPREADS
     The virus that causes COVID-19 is mainly transmitted through droplets generated when an infected person coughs, sneezes, or exhales. These droplets are too heavy to hang in the air, and quickly fall on floors or surfaces.
      You can be infected by breathing in the virus if you are within close proximity of someone who has COVID-19, or by touching a contaminated surface and then your eyes, nose or mouth.


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